Anti-SR-4 (D47) HTR4 Antibody
Boster Bio Anti-SR-4 (D47) HTR4 Antibody catalog # A03681-3. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
5-hydroxytryptamine receptor 4;5-HT-4;5-HT4; Serotonin receptor 4; HTR4;
Gene Name
HTR4
UniProt
Q13639
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 14-66 of Human SR-4.
Clonality
Polyclonal
Tissue Specificity
Isoform 5-HT4 (A) is expressed in ileum, brain, and atrium, but not in the ventricle.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
Molecular Weight
43761 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
5-hydroxytryptamine receptor 4
Subcellular Location
Cell membrane; Multi-pass membrane protein. Endosome. Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. .
Protein Name
5-hydroxytryptamine receptor 4
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