Anti-BRCA1-associated protein BRAP Antibody
Boster Bio Anti-BRCA1-associated protein BRAP Antibody catalog # A03573. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
BRCA1-associated protein;2.3.2.27
Gene Name
BRAP
UniProt
Q7Z569
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human BRAP (NP_006759.3) .
Clonality
Polyclonal
Tissue Specificity
Expressed in breast epithelial cell lines.
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Molecular Weight
67305 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
BRCA1-associated protein
Subcellular Location
Cytoplasm
Protein Name
BRCA1-associated protein
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