Anti-Bad (phospho-S136) Antibody

Boster Bio Anti-Bad (phospho-S136) Antibody catalog # A03520S136. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; BAD; BBC6, BCL2L8;

Gene Name

BAD

UniProt

Q92934

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human Bad around the phosphorylation site of Serine 136.

Clonality

Polyclonal

Tissue Specificity

Expressed in a wide variety of tissues.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity) . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. .