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Anti-Calpain 2 CAPN2 Antibody

Boster Bio Anti-Calpain 2 CAPN2 Antibody catalog # A03492-1. Tested in WB, ICC, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Calpain-2 catalytic subunit;3.4.22.53; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain; CAPN2; CANPL2;

Gene Name

CAPN2

UniProt

P17655

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, ICC, IHC, Flow Cytometry

Purification

ProA affinity purified

Form

Liquid

Function

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508) . Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity) .

Molecular Weight

79995 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Calpain-2 catalytic subunit

Subcellular Location

Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca (2+) binding.

Protein Name

Calpain-2 catalytic subunit

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