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Anti-PDE3B Antibody

Boster Bio Anti-PDE3B Antibody catalog # A03323. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

CGMP-inhibited 3',5'-cyclic phosphodiesterase B;3.1.4.17; CGIPDE1; CGIP1; Cyclic GMP-inhibited phosphodiesterase B; CGI-PDE B; PDE3B;

Gene Name

PDE3B

UniProt

Q13370

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human PDE3B (NP_000913.2) .

Clonality

Polyclonal

Tissue Specificity

Abundant in adipose tissues.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Molecular Weight

124333 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

CGMP-inhibited 3',5'-cyclic phosphodiesterase B

Subcellular Location

Membrane ; Multi-pass membrane protein .

Protein Name

CGMP-inhibited 3',5'-cyclic phosphodiesterase B

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