Anti-CLCA1 Antibody
Boster Bio Anti-CLCA1 Antibody catalog # A03318. Tested in WB, IHC, IF applications. This antibody reacts with Mouse, Rat.
Product Specifications
Synonyms
Calcium-activated chloride channel regulator 1;3.4.-.-
Gene Name
CLCA1
UniProt
A8K7I4
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant protein of human CLCA1
Clonality
Polyclonal
Tissue Specificity
Highly expressed in small intestine and colon namely in intestinal basal crypt epithelia and goblet cells, and appendix. Weakly expressed in uterus, testis and kidney. Expressed in the airways epithelium of both asthmatic and healthy patients. Expressed in the bronchial epithelium, especially in mucus- producing goblet cells. Expressed in normal turbinate mucosa and nasal polyp. Expressed in.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.
Molecular Weight
100226 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Calcium-activated chloride channel regulator 1
Subcellular Location
Secreted, extracellular space
Protein Name
Calcium-activated chloride channel regulator 1
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