Anti-PORCN Antibody
Boster Bio Anti-PORCN Antibody catalog # A03268. Tested in WB applications. This antibody reacts with Mouse, Rat.
Product Specifications
Synonyms
Protein-serine O-palmitoleoyltransferase porcupine
Gene Name
PORCN
UniProt
Q9H237
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human PORCN (NP_982299.1) .
Clonality
Polyclonal
Tissue Specificity
Isoform 1 is expressed in fetal brain, brain, amygdala, caudate nucleus, cerebellum, hippocampus, pituitary, thalamus, heart, skeletal muscle and testis. Isoform 4 is expressed in amygdala, corpus callosum, hippocampus, spinal cord, kidney, liver, lung, spleen, uterus, testis. Isoform 2 and isoform 3 are expressed in substantia negra, spinal cord, heart and lung.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.
Molecular Weight
52318 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Protein-serine O-palmitoleoyltransferase porcupine
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Protein-serine O-palmitoleoyltransferase porcupine
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