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Anti-PORCN Antibody

Boster Bio Anti-PORCN Antibody catalog # A03268. Tested in WB applications. This antibody reacts with Mouse, Rat.

Product Specifications

Synonyms

Protein-serine O-palmitoleoyltransferase porcupine

Gene Name

PORCN

UniProt

Q9H237

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein of human PORCN (NP_982299.1) .

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is expressed in fetal brain, brain, amygdala, caudate nucleus, cerebellum, hippocampus, pituitary, thalamus, heart, skeletal muscle and testis. Isoform 4 is expressed in amygdala, corpus callosum, hippocampus, spinal cord, kidney, liver, lung, spleen, uterus, testis. Isoform 2 and isoform 3 are expressed in substantia negra, spinal cord, heart and lung.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.

Molecular Weight

52318 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Protein-serine O-palmitoleoyltransferase porcupine

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Protein-serine O-palmitoleoyltransferase porcupine

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