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Anti-ABCA7 Antibody

Boster Bio Anti-ABCA7 Antibody catalog # A03163-2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

ATP-binding cassette sub-family A member 7; ABCA-SSN; Autoantigen SS-N; Macrophage ABC transporter; ABCA7;

Gene Name

ABCA7

UniProt

Q8IZY2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human ABCA7 .

Clonality

Polyclonal

Tissue Specificity

Expressed in leukocytes (at protein level) . Widely expressed. Highly expressed in myelo-lymphatic tissues including peripheral leukocytes, thymus, spleen and bone marrow. Isoform 2 is more abundant in lymph node, spleen, thymus and trachea than isoform 1 which is more strongly expressed in brain and bone marrow.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.

Molecular Weight

234350 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03163-2

Product MSDS

https://www.bosterbio.com/msds?sku=A03163-2

Other Gene Names

ATP-binding cassette sub-family A member 7

Subcellular Location

Cell membrane

Protein Name

ATP-binding cassette sub-family A member 7

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