Anti-ABCA7 Antibody
Boster Bio Anti-ABCA7 Antibody catalog # A03163-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
ATP-binding cassette sub-family A member 7; ABCA-SSN; Autoantigen SS-N; Macrophage ABC transporter; ABCA7;
Gene Name
ABCA7
UniProt
Q8IZY2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ABCA7.
Clonality
Polyclonal
Tissue Specificity
Expressed in leukocytes (at protein level) . Widely expressed. Highly expressed in myelo-lymphatic tissues including peripheral leukocytes, thymus, spleen and bone marrow. Isoform 2 is more abundant in lymph node, spleen, thymus and trachea than isoform 1 which is more strongly expressed in brain and bone marrow.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.
Molecular Weight
234350 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
ATP-binding cassette sub-family A member 7
Subcellular Location
Cell membrane
Protein Name
ATP-binding cassette sub-family A member 7
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