Anti-SLC22A4 Antibody
Boster Bio Anti-SLC22A4 Antibody catalog # A03032. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Solute carrier family 22 member 4; Ergothioneine transporter; ET transporter; Organic cation/carnitine transporter 1; SLC22A4; ETT, OCTN1, UT2H;
Gene Name
SLC22A4
UniProt
Q9H015
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human SLC22A4
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Highly expressed in whole blood, bone marrow, trachea and fetal liver. Weakly expressed in kidney, skeletal muscle, prostate, lung, pancreas, placenta, heart, uterus, spleen and spinal cord. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. Predominantly expressed in CD14 cells in peripheral blood mononuclear cells.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET) .
Molecular Weight
62155 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Solute carrier family 22 member 4
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Name
Solute carrier family 22 member 4
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