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Anti-SRA1 Antibody

Boster Bio Anti-SRA1 Antibody catalog # A02942-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Steroid receptor RNA activator 1; Steroid receptor RNA activator protein; SRAP; SRA1

Gene Name

SRA1

UniProt

Q9HD15

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human SRA1.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up- regulated in human tumors of the breast, ovary, and uterus.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2) . Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.

Molecular Weight

25673 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Steroid receptor RNA activator 1

Subcellular Location

Nucleus

Protein Name

Steroid receptor RNA activator 1

Frequently Asked Questions

More Discoveries

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