Anti-Ataxin-7 ATXN7 Antibody
Boster Bio Anti-Ataxin-7 ATXN7 Antibody catalog # A02936. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Ataxin-7; Spinocerebellar ataxia type 7 protein; ATXN7; SCA7;
Gene Name
ATXN7
UniProt
O15265
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human ATXN7.
Clonality
Polyclonal
Tissue Specificity
Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymphoblast and intestine.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization.
Molecular Weight
95451 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Ataxin-7
Subcellular Location
Isoform a: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm.
Protein Name
Ataxin-7
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