Anti-TACC3 Antibody
Boster Bio Anti-TACC3 Antibody catalog # A02876-1. Tested in WB, ICC/IF, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Transforming acidic coiled-coil-containing protein 3; ERIC-1; TACC3; ERIC1;
Gene Name
TACC3
UniProt
Q9Y6A5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, ICC, IF, IHC
Purification
ProA affinity purified
Form
Liquid
Function
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity) . Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825) . May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476) .
Molecular Weight
90360 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Transforming acidic coiled-coil-containing protein 3
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Protein Name
Transforming acidic coiled-coil-containing protein 3
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