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Anti-GluR1 (phospho-S849) GRIA1 Antibody

Boster Bio Anti-GluR1 (phospho-S849) GRIA1 Antibody catalog # A02677S849. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1; GRIA1; GLUH1, GLUR1;

Gene Name

GRIA1

UniProt

P42261

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human GluR1 around the phosphorylation site of Serine 849.

Clonality

Polyclonal

Tissue Specificity

Widely expressed in brain.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Molecular Weight

101506 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02677S849

Product MSDS

https://www.bosterbio.com/msds?sku=A02677S849

Other Gene Names

Glutamate receptor 1

Subcellular Location

Cell membrane

Protein Name

Glutamate receptor 1

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