Anti-Renin Receptor ATP6AP2 Antibody
Boster Bio Anti-Renin Receptor ATP6AP2 Antibody catalog # A02665-1. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Renin receptor; ATPase H (+) -transporting lysosomal accessory protein 2; ATPase H (+) -transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryonic liver differentiation factor 10; N14F; Renin/prorenin receptor; Vacuolar ATP synthase membrane sector-associated protein M8-9; ATP6M8-9; V-ATPase M8.9 subunit; ATP6AP2; ATP6IP2, CAPER, ELDF10; HT028, MSTP009, PSEC0072;
Gene Name
ATP6AP2
UniProt
O75787
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 209-254 of Human Renin Receptor.
Clonality
Polyclonal
Tissue Specificity
Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) .
Molecular Weight
39008 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A02665-1
Product MSDS
https://www.bosterbio.com/msds?sku=A02665-1
Other Gene Names
Renin receptor
Subcellular Location
Membrane ; Single-pass type I membrane protein .
Protein Name
Renin receptor
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