Anti-SLC11A2 Antibody
Boster Bio Anti-SLC11A2 Antibody catalog # A02622. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Natural resistance-associated macrophage protein 2; NRAMP 2; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Solute carrier family 11 member 2; SLC11A2; DCT1, DMT1, NRAMP2; OK/SW-cl.20;
Gene Name
SLC11A2
UniProt
P49281
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human DMT1/SLC11A2 (NP_001167597.1) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed. Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in spleen, thymus and pancreas. Isoform 3 and isoform 4 are abundantly expressed in duodenum and kidney.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
Molecular Weight
62266 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Natural resistance-associated macrophage protein 2
Subcellular Location
Isoform 2: Cell membrane
Protein Name
Natural resistance-associated macrophage protein 2
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