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Anti-NOTCH4 Antibody

Boster Bio Anti-NOTCH4 Antibody catalog # A02582. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Neurogenic locus notch homolog protein 4; Notch 4; hNotch4; Notch 4 extracellular truncation; Notch 4 intracellular domain; NOTCH4; INT3;

Gene Name

NOTCH4

UniProt

Q99466

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.

Applications

WB, Flow Cytometry

Purification

ProA affinity purified

Form

Liquid

Function

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity) . .

Molecular Weight

209622 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02582

Product MSDS

https://www.bosterbio.com/msds?sku=A02582

Other Gene Names

Neurogenic locus notch homolog protein 4

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

Neurogenic locus notch homolog protein 4

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