Anti-NOTCH4 Antibody
Boster Bio Anti-NOTCH4 Antibody catalog # A02582. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Neurogenic locus notch homolog protein 4; Notch 4; hNotch4; Notch 4 extracellular truncation; Notch 4 intracellular domain; NOTCH4; INT3;
Gene Name
NOTCH4
UniProt
Q99466
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.
Applications
WB, Flow Cytometry
Purification
ProA affinity purified
Form
Liquid
Function
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity) . .
Molecular Weight
209622 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Neurogenic locus notch homolog protein 4
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Name
Neurogenic locus notch homolog protein 4
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