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Anti-MBD3 Antibody

Boster Bio Anti-MBD3 Antibody catalog # A02571-1. Tested in WB, ICC, IF, IHC, Flow Cytometry, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3; MBD3;

Gene Name

MBD3

UniProt

O95983

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Applications

WB, ICC, IF, IHC, Flow Cytometry, IP

Purification

ProA affinity purified

Form

Liquid

Function

Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384) . Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro) . Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175) . Recruits histone deacetylases and DNA methyltransferases.

Molecular Weight

32844 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Methyl-CpG-binding domain protein 3

Subcellular Location

Nucleus. Chromosome. Nuclear, in discrete foci. Detected on chromatin, at promoter regions of active genes.

Protein Name

Methyl-CpG-binding domain protein 3

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