Anti-MBD3 Antibody
Boster Bio Anti-MBD3 Antibody catalog # A02571-1. Tested in WB, ICC, IF, IHC, Flow Cytometry, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3; MBD3;
Gene Name
MBD3
UniProt
O95983
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, ICC, IF, IHC, Flow Cytometry, IP
Purification
ProA affinity purified
Form
Liquid
Function
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384) . Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro) . Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175) . Recruits histone deacetylases and DNA methyltransferases.
Molecular Weight
32844 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Methyl-CpG-binding domain protein 3
Subcellular Location
Nucleus. Chromosome. Nuclear, in discrete foci. Detected on chromatin, at promoter regions of active genes.
Protein Name
Methyl-CpG-binding domain protein 3
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