Anti-FPR1 (I207) Antibody
Boster Bio Anti-FPR1 (I207) Antibody catalog # A02509-3. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
FMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor; FPR1;
Gene Name
FPR1
UniProt
P21462
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to the 207-252 of Human FPR1.
Clonality
Polyclonal
Tissue Specificity
Neutrophils.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520) . Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520) . This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (PubMed:1712023, PubMed:10514456) .
Molecular Weight
38446 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
FMet-Leu-Phe receptor
Subcellular Location
Cell membrane
Protein Name
FMet-Leu-Phe receptor
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