Anti-CD207 Antibody
Boster Bio Anti-CD207 Antibody catalog # A02316-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
C-type lectin domain family 4 member K; Langerin; CD207; CD207; CLEC4K;
Gene Name
CD207
UniProt
Q9UJ71
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human Langerin/CD207 (NP_056532.4) .
Clonality
Polyclonal
Tissue Specificity
Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs) ; is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Molecular Weight
36725 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
C-type lectin domain family 4 member K
Subcellular Location
Membrane
Protein Name
C-type lectin domain family 4 member K
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