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Anti-ADAM12 Antibody

Boster Bio Anti-ADAM12 Antibody catalog # A02264. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Disintegrin and metalloproteinase domain-containing protein 12; ADAM 12;3.4.24.-; Meltrin-alpha; ADAM12; MLTN; UNQ346/PRO545;

Gene Name

ADAM12

UniProt

O43184

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human ADAM12

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity) . .

Molecular Weight

99542 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Disintegrin and metalloproteinase domain-containing protein 12

Subcellular Location

Isoform 1: Cell membrane; Single-pass type I membrane protein.

Protein Name

Disintegrin and metalloproteinase domain-containing protein 12

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