Anti-G3BP-1 (phospho-S232) Antibody
Boster Bio Anti-G3BP-1 (phospho-S232) Antibody catalog # A02199S232. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Ras GTPase-activating protein-binding protein 1; G3BP-1;3.6.4.12
Gene Name
G3BP1
UniProt
Q13283
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human G3BP-1 around the phosphorylation site of Serine 232.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
IHC: 1:50-1:200
Form
Liquid
Function
ATP- and magnesium-dependent helicase (PubMed:9889278) . Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends (PubMed:9889278) . Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency (PubMed:9889278) . Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA (PubMed:9889278) . Phosphorylation-dependent sequence-specific endoribonuclease in vitro (PubMed:11604510) . Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR (PubMed:11604510) . May be a regulated effector of stress granule assembly (PubMed:12642610, PubMed:20180778) .
Molecular Weight
52164 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Ras GTPase-activating protein-binding protein 1
Subcellular Location
Cytoplasm, cytosol
Protein Name
Ras GTPase-activating protein-binding protein 1
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