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Anti-G3BP-1 (D226) Antibody

Boster Bio Anti-G3BP-1 (D226) Antibody catalog # A02199-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Ras GTPase-activating protein-binding protein 1; G3BP-1;3.6.4.12

Gene Name

G3BP1

UniProt

Q13283

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthetic peptide, corresponding to amino acids 196-246 of Human G3BP-1.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

ATP- and magnesium-dependent helicase (PubMed:9889278) . Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends (PubMed:9889278) . Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency (PubMed:9889278) . Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA (PubMed:9889278) . Phosphorylation-dependent sequence-specific endoribonuclease in vitro (PubMed:11604510) . Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR (PubMed:11604510) . May be a regulated effector of stress granule assembly (PubMed:12642610, PubMed:20180778) .

Molecular Weight

52164 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Ras GTPase-activating protein-binding protein 1

Subcellular Location

Cytoplasm, cytosol

Protein Name

Ras GTPase-activating protein-binding protein 1

Frequently Asked Questions

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