Anti-TAF1 Antibody
Boster Bio Anti-TAF1 Antibody catalog # A02151-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Transcription initiation factor TFIID subunit 1;2.3.1.48
Gene Name
TAF1
UniProt
P21675
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding Human TAF1.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Largest component and core scaffold of the TFIID basal transcription factor complex (PubMed:25412659, PubMed:27007846) . Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2- mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity (PubMed:25412659) . Essential for progression of the G1 phase of the cell cycle (PubMed:11278496, PubMed:15053879, PubMed:2038334, PubMed:8450888, PubMed:8625415, PubMed:9660973, PubMed:9858607) . Exhibits histone acetyltransferase activity towards histones H3 and H4 (PubMed:15870300) .
Molecular Weight
212677 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Transcription initiation factor TFIID subunit 1
Subcellular Location
Nucleus
Protein Name
Transcription initiation factor TFIID subunit 1
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