Anti-AR-Alpha 1A (Q365) ADRA1A Antibody
Boster Bio Anti-AR-Alpha 1A (Q365) ADRA1A Antibody catalog # A02110. Tested in WB, IHC, IF applications. This antibody reacts with Human.
Product Specifications
Synonyms
Alpha-1A adrenergic receptor; Alpha-1A adrenoreceptor; Alpha-1A adrenoceptor; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c; ADRA1A; ADRA1C;
Gene Name
ADRA1A
UniProt
P35348
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 350-400 of Human AR-α1A.
Clonality
Polyclonal
Tissue Specificity
Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G (q) and G (11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE) -stimulated ERK signaling in cardiac myocytes.
Molecular Weight
51487 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Alpha-1A adrenergic receptor
Subcellular Location
Nucleus membrane; Multi-pass membrane protein. Cell membrane
Protein Name
Alpha-1A adrenergic receptor
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