Anti-Exostosin-1 EXT1 Antibody
Boster Bio Anti-Exostosin-1 EXT1 Antibody catalog # A02086. Tested in IHC, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Exostosin-1;2.4.1.224;2.4.1.225; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses protein 1; Putative tumor suppressor protein EXT1; EXT1;
Gene Name
EXT1
UniProt
Q16394
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic peptide derived from human EXT1:651-746/746
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
IHC, IF, ICC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413) .
Molecular Weight
86255 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Exostosin-1
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Exostosin-1
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