Anti-CD321/JAM-A F11R Antibody
Boster Bio Anti-CD321/JAM-A F11R Antibody catalog # A02068-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321; F11R; JAM1, JCAM; UNQ264/PRO301;
Gene Name
F11R
UniProt
Q9Y624
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Expressed in endothelium, epithelium and leukocytes (at protein level) .
Applications
WB, IHC
Purification
ProA affinity purified
Form
Liquid
Function
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913) . The association of the PARD6- PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity) . Ligand for integrin alpha- L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992) . Involved in platelet activation (PubMed:10753840) .
Molecular Weight
32583 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A02068-1
Product MSDS
https://www.bosterbio.com/msds?sku=A02068-1
Other Gene Names
Junctional adhesion molecule A
Subcellular Location
Cell junction, tight junction
Protein Name
Junctional adhesion molecule A
Curated Selection
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