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Anti-OCRL Antibody

Boster Bio Anti-OCRL Antibody catalog # A02042-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Inositol polyphosphate 5-phosphatase OCRL-1;3.1.3.36; Lowe oculocerebrorenal syndrome protein; OCRL; INPP5F, OCRL1;

Gene Name

OCRL

UniProt

Q01968

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human OCRL (NP_001578.2) .

Clonality

Polyclonal

Tissue Specificity

Brain, skeletal muscle, heart, kidney, lung, placenta and fibroblasts. Expressed in the retina and the retinal pigment epithelium.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698) . May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976) .

Molecular Weight

104205 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Inositol polyphosphate 5-phosphatase OCRL-1

Subcellular Location

Cytoplasmic vesicle, phagosome membrane

Protein Name

Inositol polyphosphate 5-phosphatase OCRL-1

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