Anti-Na+ CP type VIII Alpha SCN8A Antibody
Boster Bio Anti-Na+ CP type VIII Alpha SCN8A Antibody catalog # A02015. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.6; SCN8A; MED;
Gene Name
SCN8A
UniProt
Q9UQD0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human Na+ CP type VIIIα.
Clonality
Polyclonal
Tissue Specificity
Isoform 5 is expressed in non-neuronal tissues, such as monocytes/macrophages.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
Molecular Weight
225280 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Sodium channel protein type 8 subunit alpha
Subcellular Location
Cell membrane
Protein Name
Sodium channel protein type 8 subunit alpha
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