Anti-DAP12 TYROBP Antibody
Boster Bio Anti-DAP12 TYROBP Antibody catalog # A01996. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human.
Product Specifications
Synonyms
TYRO protein tyrosine kinase-binding protein; DNAX-activation protein 12; Killer-activating receptor-associated protein; KAR-associated protein; TYROBP; DAP12, KARAP;
Gene Name
TYROBP
UniProt
O43914
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide within human DAP12 aa 60-100.
Clonality
Polyclonal
Tissue Specificity
Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Expressed in hematological cells and tissues such as peripheral blood leukocytes and spleen. Also found in bone marrow, lymph nodes, placenta, lung and liver. Expressed at lower levels in different parts of the brain especially in the basal ganglia and corpus callosum.
Applications
WB, IHC, Flow Cytometry
Purification
ProA affinity purified
Form
Liquid
Function
Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.
Molecular Weight
12179 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
TYRO protein tyrosine kinase-binding protein
Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Name
TYRO protein tyrosine kinase-binding protein
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