Anti-Actinin Alpha 4 ACTN4 Antibody
Boster Bio Anti-Actinin Alpha 4 ACTN4 Antibody catalog # A01975. Tested in WB, ICC, IF, IP, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Alpha-actinin-4 ; Non-muscle alpha-actinin 4
Gene Name
ACTN4
UniProt
O43707
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
WB, ICC, IF, IP, IHC, Flow Cytometry
Purification
ProA affinity purified
Form
Liquid
Function
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable) . Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161) . Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity) . May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778) .
Molecular Weight
104854 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A01975
Product MSDS
https://www.bosterbio.com/msds?sku=A01975
Other Gene Names
Alpha-actinin-4
Subcellular Location
Nucleus
Protein Name
Alpha-actinin-4
Curated Selection
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