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Anti-Actinin Alpha 4 ACTN4 Antibody

Boster Bio Anti-Actinin Alpha 4 ACTN4 Antibody catalog # A01975. Tested in WB, ICC, IF, IP, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Alpha-actinin-4 ; Non-muscle alpha-actinin 4

Gene Name

ACTN4

UniProt

O43707

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

WB, ICC, IF, IP, IHC, Flow Cytometry

Purification

ProA affinity purified

Form

Liquid

Function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable) . Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161) . Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity) . May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778) .

Molecular Weight

104854 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01975

Product MSDS

https://www.bosterbio.com/msds?sku=A01975

Other Gene Names

Alpha-actinin-4

Subcellular Location

Nucleus

Protein Name

Alpha-actinin-4

Curated Selection

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