Anti-C5aR (S334) C5AR1 Antibody
Boster Bio Anti-C5aR (S334) C5AR1 Antibody catalog # A01898S334. Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD88; C5AR1; C5AR, C5R1;
Gene Name
C5AR1
UniProt
P21730
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 300-350 of Human C5aR.
Clonality
Polyclonal
Applications
IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009) . The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099) . Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520) .
Molecular Weight
39336 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
C5a anaphylatoxin chemotactic receptor 1
Subcellular Location
Cell membrane
Protein Name
C5a anaphylatoxin chemotactic receptor 1
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