Anti-Midkine MDK Antibody
Boster Bio Anti-Midkine MDK Antibody catalog # A01823-1. Tested in WB, IHC, IP applications. This antibody reacts with Human.
Product Specifications
Synonyms
Midkine; MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MK1, NEGF2;
Gene Name
MDK
UniProt
P21741
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions.
Applications
WB, IHC, IP
Purification
ProA affinity purified
Form
Liquid
Function
Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity) .
Molecular Weight
15585 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Midkine
Subcellular Location
Secreted.
Protein Name
Midkine
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