Anti-NMDA Zeta 1 (S885) GRIN1 Antibody
Boster Bio Anti-NMDA Zeta 1 (S885) GRIN1 Antibody catalog # A01808S885. Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Glutamate receptor ionotropic, NMDA 1; GluN1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; GRIN1; NMDAR1;
Gene Name
GRIN1
UniProt
Q05586
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 860-910 of Human NMDAζ1.
Clonality
Polyclonal
Applications
IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg (2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280) . Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761) .
Molecular Weight
105373 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A01808S885
Product MSDS
https://www.bosterbio.com/msds?sku=A01808S885
Other Gene Names
Glutamate receptor ionotropic, NMDA 1
Subcellular Location
Cell membrane
Protein Name
Glutamate receptor ionotropic, NMDA 1
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