Anti-TXNRD1 Antibody
Boster Bio Anti-TXNRD1 Antibody catalog # A01778-1. Tested in WB, ICC, IHC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Thioredoxin reductase 1, cytoplasmic; TR;1.8.1.9; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; TXNRD1; GRIM12, KDRF;
Gene Name
TXNRD1
UniProt
Q16881
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Isoform 1 is expressed predominantly in Leydig cells (at protein level) . Also expressed in ovary, spleen, heart, liver, kidney and pancreas and in a number of cancer cell lines. Isoform 4 is widely expressed with highest levels in kidney, testis, uterus, ovary, prostate, placenta and fetal liver.
Applications
WB, ICC, IHC, IP, Flow Cytometry
Purification
ProA affinity purified
Form
Liquid
Function
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Molecular Weight
70906 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A01778-1
Product MSDS
https://www.bosterbio.com/msds?sku=A01778-1
Other Gene Names
Thioredoxin reductase 1, cytoplasmic
Subcellular Location
Cytoplasm .
Protein Name
Thioredoxin reductase 1, cytoplasmic
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