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Anti-Tropomyosin 1 TPM1 Antibody

Boster Bio Anti-Tropomyosin 1 TPM1 Antibody catalog # A01591-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1; TPM1; C15orf13, TMSA;

Gene Name

TPM1

UniProt

P09493

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human Tropomyosin 1 aa 100-300.

Clonality

Polyclonal

Tissue Specificity

Detected in primary breast cancer tissues but undetectable in normal breast tissues in Sudanese patients. Isoform 1 is expressed in adult and fetal skeletal muscle and cardiac tissues, with higher expression levels in the cardiac tissues. Isoform 10 is expressed in adult and fetal cardiac tissues, but not in skeletal muscle.

Applications

WB, IHC, Flow Cytometry

Purification

ProA affinity purified

Form

Liquid

Function

Binds to actin filaments in muscle and non-muscle cells (PubMed:23170982) . Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (PubMed:23170982) . Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

Molecular Weight

32709 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01591-2

Product MSDS

https://www.bosterbio.com/msds?sku=A01591-2

Other Gene Names

Tropomyosin alpha-1 chain

Subcellular Location

Cytoplasm, cytoskeleton

Protein Name

Tropomyosin alpha-1 chain

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