Anti-Tropomyosin 1 TPM1 Antibody
Boster Bio Anti-Tropomyosin 1 TPM1 Antibody catalog # A01591-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1; TPM1; C15orf13, TMSA;
Gene Name
TPM1
UniProt
P09493
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human Tropomyosin 1 aa 100-300.
Clonality
Polyclonal
Tissue Specificity
Detected in primary breast cancer tissues but undetectable in normal breast tissues in Sudanese patients. Isoform 1 is expressed in adult and fetal skeletal muscle and cardiac tissues, with higher expression levels in the cardiac tissues. Isoform 10 is expressed in adult and fetal cardiac tissues, but not in skeletal muscle.
Applications
WB, IHC, Flow Cytometry
Purification
ProA affinity purified
Form
Liquid
Function
Binds to actin filaments in muscle and non-muscle cells (PubMed:23170982) . Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (PubMed:23170982) . Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Molecular Weight
32709 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Tropomyosin alpha-1 chain
Subcellular Location
Cytoplasm, cytoskeleton
Protein Name
Tropomyosin alpha-1 chain
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