Anti-RPGR Antibody
Boster Bio Anti-RPGR Antibody catalog # A01522-1. Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
X-linked retinitis pigmentosa GTPase regulator; RPGR; RP3, XLRP3;
Gene Name
RPGR
UniProt
Q92834
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from Human RPGR (Accession Q92834), corresponding to amino acid residues L986-N1009.
Clonality
Polyclonal
Tissue Specificity
Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.
Applications
WB, IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity) . May be involved in microtubule organization and regulation of transport in primary cilia.
Molecular Weight
113387 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
X-linked retinitis pigmentosa GTPase regulator
Subcellular Location
Cytoplasm, cytoskeleton, flagellum axoneme
Protein Name
X-linked retinitis pigmentosa GTPase regulator
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