Anti-Transcription factor HES-1 Hes1 Antibody
Boster Bio Anti-Transcription factor HES-1 Hes1 Antibody catalog # A01459. Tested in WB, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Transcription factor HES-1; Class B basic helix-loop-helix protein 39; bHLHb39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like protein; hHL; HES1; BHLHB39, HL, HRY;
Gene Name
HES1
UniProt
Q14469
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, ICC, IF, IHC, Flow Cytometry
Purification
ProA affinity purified
Form
Liquid
Function
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity) . May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Molecular Weight
29541 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Transcription factor HES-1
Subcellular Location
Nucleus.
Protein Name
Transcription factor HES-1
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