Anti-Dermcidin DCD Antibody

Boster Bio Anti-Dermcidin DCD Antibody catalog # A01446. Tested in WB, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Dermcidin;3.4.-.-; Preproteolysin; Survival-promoting peptide; DCD-1; DCD; AIDD, DSEP;

Gene Name

DCD

UniProt

P81605

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from Human DCD, corresponding to amino acid residues G69-K96.

Clonality

Polyclonal

Tissue Specificity

Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues (PubMed:17448443) .