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Anti-Cytokeratin 14 KRT14 Antibody

Boster Bio Anti-Cytokeratin 14 KRT14 Antibody catalog # A01432-2. Tested in WB, ICC/IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Keratin, type I cytoskeletal 14; Cytokeratin-14; CK-14; Keratin-14; K14; KRT14;

Gene Name

KRT14

UniProt

P02533

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.

Applications

WB, ICC, IF, IHC

Purification

ProA affinity purified

Form

Liquid

Function

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

Molecular Weight

51561 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Keratin, type I cytoskeletal 14

Subcellular Location

Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.

Protein Name

Keratin, type I cytoskeletal 14

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