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Anti-Cytokeratin 18 (T410) KRT18 Antibody

Boster Bio Anti-Cytokeratin 18 (T410) KRT18 Antibody catalog # A01357T410. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18; KRT18; CYK18; PIG46;

Gene Name

KRT18

UniProt

P05783

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 381-430 of Human Cytokeratin 18.

Clonality

Polyclonal

Tissue Specificity

Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.

Molecular Weight

48058 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01357T410

Product MSDS

https://www.bosterbio.com/msds?sku=A01357T410

Other Gene Names

Keratin, type I cytoskeletal 18

Subcellular Location

Cytoplasm, perinuclear region. Nucleus, nucleolus.

Protein Name

Keratin, type I cytoskeletal 18

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