Anti-Hepcidin HAMP Antibody
Boster Bio Anti-Hepcidin HAMP Antibody catalog # A01347. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Hepcidin; Liver-expressed antimicrobial peptide 1; LEAP-1; Putative liver tumor regressor; PLTR; Hepcidin-25; Hepc25; Hepcidin-20; Hepc20; HAMP; HEPC, LEAP1; UNQ487/PRO1003;
Gene Name
HAMP
UniProt
P81172
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.
Applications
WB, IHC
Purification
ProA affinity purified
Form
Liquid
Function
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005) .
Molecular Weight
9408 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A01347
Product MSDS
https://www.bosterbio.com/msds?sku=A01347
Other Gene Names
Hepcidin
Subcellular Location
Secreted.
Protein Name
Hepcidin
Curated Selection
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