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Anti-Thrombomodulin THBD Antibody

Boster Bio Anti-Thrombomodulin THBD Antibody catalog # A01325-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM;

Gene Name

THBD

UniProt

P07204

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 530-575 of Human Thrombomodulin.

Clonality

Polyclonal

Tissue Specificity

Endothelial cells are unique in synthesizing thrombomodulin.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Molecular Weight

60329 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Thrombomodulin

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Thrombomodulin

Frequently Asked Questions

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