Anti-Thrombomodulin THBD Antibody
Boster Bio Anti-Thrombomodulin THBD Antibody catalog # A01325-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM;
Gene Name
THBD
UniProt
P07204
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 530-575 of Human Thrombomodulin.
Clonality
Polyclonal
Tissue Specificity
Endothelial cells are unique in synthesizing thrombomodulin.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Molecular Weight
60329 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Thrombomodulin
Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Name
Thrombomodulin
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