Anti-N-CoR (H76) NCOR1 Antibody

Boster Bio Anti-N-CoR (H76) NCOR1 Antibody catalog # A01304. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Nuclear receptor corepressor 1; N-CoR; N-CoR1; NCOR1; KIAA1047;

Gene Name

NCOR1

UniProt

O75376

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 51-100 of Human N-CoR.

Clonality

Polyclonal

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Mediates transcriptional repression by certain nuclear receptors (PubMed:20812024) . Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024) .