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Anti-mSin3A Antibody

Boster Bio Anti-mSin3A Antibody catalog # A01203-1. Tested in WB, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Paired amphipathic helix protein Sin3a; Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a; SIN3A

Gene Name

SIN3A

UniProt

Q96ST3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Applications

WB, ICC, IF, IHC, Flow Cytometry

Purification

ProA affinity purified

Form

Liquid

Function

Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity) .

Molecular Weight

145175 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01203-1

Product MSDS

https://www.bosterbio.com/msds?sku=A01203-1

Other Gene Names

Paired amphipathic helix protein Sin3a

Subcellular Location

Nucleus

Protein Name

Paired amphipathic helix protein Sin3a

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