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Anti-XPA (H244) Antibody

Boster Bio Anti-XPA (H244) Antibody catalog # A01182-3. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

DNA repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein; XPA; XPAC;

Gene Name

XPA

UniProt

P23025

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 215-260 of Human XPA.

Clonality

Polyclonal

Tissue Specificity

Expressed in various cell lines and in skin fibroblasts.

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

IHC: 1:50-1:200

Form

Liquid

Function

Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.

Molecular Weight

31368 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01182-3

Product MSDS

https://www.bosterbio.com/msds?sku=A01182-3

Other Gene Names

DNA repair protein complementing XP-A cells

Subcellular Location

Nucleus

Protein Name

DNA repair protein complementing XP-A cells

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