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Anti-FCGR3B Antibody

Boster Bio Anti-FCGR3B Antibody catalog # A01177. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD16b; FCGR3B; CD16B, FCG3, FCGR3, IGFR3;

Gene Name

FCGR3B

UniProt

O75015

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human FCGR3B (NP_000561.3) .

Clonality

Polyclonal

Tissue Specificity

Expressed specifically by polymorphonuclear leukocytes (neutrophils) . Also expressed by stimulated eosinophils.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Molecular Weight

26216 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01177

Product MSDS

https://www.bosterbio.com/msds?sku=A01177

Other Gene Names

Low affinity immunoglobulin gamma Fc region receptor III-B

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Secreted after cleavage.

Protein Name

Low affinity immunoglobulin gamma Fc region receptor III-B

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