Anti-FCGR3B Antibody
Boster Bio Anti-FCGR3B Antibody catalog # A01177. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD16b; FCGR3B; CD16B, FCG3, FCGR3, IGFR3;
Gene Name
FCGR3B
UniProt
O75015
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human FCGR3B (NP_000561.3) .
Clonality
Polyclonal
Tissue Specificity
Expressed specifically by polymorphonuclear leukocytes (neutrophils) . Also expressed by stimulated eosinophils.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Molecular Weight
26216 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Low affinity immunoglobulin gamma Fc region receptor III-B
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Secreted after cleavage.
Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-B
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